Adverse Event reporting information can be found in footer

Request a Meeting

MODE OF ACTION

ONLY PENTASA® HAS ETHYL CELLULOSE COATED MICROGRANULES AND TIME DEPENDENT RELEASE1-11

Therefore PENTASA® continuously delivers mesalazine throughout the entire colon at all enteral pH conditions2

 

PENTASA® formulations consist of hundreds of ethyl cellulose coated microgranules, which pass through the stomach into the duodenum.
These spread throughout the small and large bowel releasing mesalazine in a time-dependent manner, independent of intraluminal pH.1,2,12-16

Other mesalazine formulations are pH-dependent, releasing 5-ASA from the mid to distal ileum downward where the pH is ≥6.1-11

  • Wilding IR, et al. Aliment Pharmacol Ther. 2000;14:163-169.
  • Pentasa Slow Release Tablets 500 mg. SmPC.
  • Octasa 400 mg MR Tablets. SmPC.
  • Salofalk 500 mg Gastro-resistant Prolonged Release Granules. SmPC.
  • Asacol 400 mg MR Tablets. SmPC.
  • Mezavant XL 1200 mg Gastro-resistant Prolonged Release Tablets. SmPC.
  • Sulfalazine 250 mg/5 ml Oral Suspension. SmPC.
  • Salazopyrin Tablets. SmPC.
  • Colazide 750 mg Capsules. SmPC.
  • Olsalazine Sodium 250 mg Capsules. SmPC.
  • Ye B and van Langenberg DR. World J Gastrointest Pharmacol Ther. 2015;6:137–44.
  • Pentasa Slow Release Tablets 1 g. SmPC.
  • Pentasa Sachet 1 g. SmPC.
  • Pentasa Sachet 2 g. SmPC.
  • Pentasa Sachet 4 g. SmPC.
  • Pentasa Enema 1 g. SmPC.
Impact of Non-Adherence
Pentasa in Paediatrics
Pentasa in Adults
Resources

Job Code: UK-PA-2300006 - Date of preparation: November 2023

cookiepopup

Our use of cookies

We use cookies (including third party cookies) to collect data while you use this website in order to make it work, keep it secure and comply with regulations. We’d also like your consent to use cookies so we can provide you with tailored content and advertising and analyse how you and other people use the website.

Select “On” to consent to our use of these cookies and continue to the website, or select “Off” to control which types of cookies we use. You can read more about cookies in our Privacy Policy.

Necessary cookies

Necessary cookies enable core functionality such as security, network management, and accessibility. You may disable these by changing your browser settings, but this may affect how the website functions.

Analytics cookies

We’d like to set Google Analytics cookies to help us to improve our website by collecting and reporting information on how you use it. The cookies collect information in away that does not directly identify anyone. For more information on how these cookies work, please see our Privacy Policy.