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PENTASA®’s unique ethyl cellulose coated microgranules release mesalazine independent of intestinal pH1,8-16 and food co-administration3-5


Pentasa is indicated for the induction and maintenance of remission in mild to moderate Ulcerative Colitis.

PENTASA® (500mg tablets, 1g, 2g and 4g sachets) is licensed in children 6 years of age and older, and given in divided doses.

Adding to its uniqueness, PENTASA once-daily sachets can now be added to yoghurt; providing your mild to moderate UC patients with a simple dosing regimen that can fit easily into their daily routine.3-5


Additionally PENTASA OD oral dosing:
  • Achieves symptom remission faster than BD PENTASA dosing and maintains remission for 12 months*17-18
  • Is effective throughout the entire colon, including left sided disease*17-19
  • Achieves significantly better mucosal healing than BD PENTASA dosing in 8 weeks and is maintained over 12 months*17-18

*Included once-daily PENTASA enema for the first 4 weeks

  • Pentasa Slow Release Tablets 500 mg. SmPC.
  • Pentasa Slow Release Tablets 1 g. SmPC.
  • Pentasa Sachet 1 g. SmPC.
  • Pentasa Sachet 2 g. SmPC.
  • Pentasa Sachet 4 g. SmPC.
  • Pentasa Enema 1 g. SmPC.
  • Pentasa Suppositories 1 g. SmPC.
  • Octasa 400 mg MR Tablets. SmPC.
  • Salofalk 500 mg Gastro-resistant Prolonged Release Granules. SmPC.
  • Asacol 400 mg MR Tablets. SmPC.
  • Mezavant XL 1200 mg Gastro-resistant Prolonged Release Tablets. SmPC.
  • Sulfalazine 250 mg/5 ml Oral Suspension. SmPC.
  • Salazopyrin En-Tabs. SmPC.
  • Salazopyrin Tablets. SmPC.
  • Colazide 750 mg Capsules. SmPC.
  • Olsalazine Sodium 250 mg Capsules. SmPC.
  • Flourie B, et al. Aliment Pharmacol Ther. 2013;37(8):767–75.
  • Dignass AU, et al. Clin. Gastroenterol Hepatol. 2009;7(7):762–9.
  • Bokemeyer B, et al. J Crohn’s Colitis. 2012;6:476-82.
  • Probert C.S.J, et al. J Crohn’s Colitis. 2014;8:200–7.
  • Marteau P, et al. Gut. 2005;54(7):960–5.

Job Code: UK-PA-2300006 - Date of preparation: November 2023


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