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PENTASA® FORMULATIONS

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PENTASA® FORMULATIONS

PENTASA®’s range of formulations give your patients a choice2-5,10-12

High dose* once-daily dosing provides a simple route to remission1-11

The range of oral and rectal formulations shown below can be used in adults.
For guidance on the use of Pentasa® in paediatrics click here.

ORAL FORMULATIONS

4g-sachets-web
4g sachet
4g-sachets-web
2g sachet
4g-sachets-web
1g sachet
4g-sachets-web
1g tablet
4g-sachets-web
500mg tablet

RECTAL FORMULATIONS

4g-sachets-web
1g enema
4g-sachets-web
1g suppository

*1g tablets, 1g, 2g and 4g sachets.

Images do not show medication at actual size.

HIGH DOSE* ONCE-DAILY DOSING PROVIDES A SIMPLE ROUTE TO REMISSION1-11

High-dose formulation* reduces  pill burden compared to PENTASA® 500 mg tablets2,5-12

Once-daily dosing is likely to improve convenience & adherence13

ACHIEVING REMISSION:
Doses-for-Remission-2-4g

1 x 4g PENTASA® sachet5

4 x 1g PENTASA® tablets2

PENTASA® tablets can be dispersed in cold water to facilitate swallowing12

MAINTAINING REMISSION:
Doses-for-Remission-2-4g

1 x 2g PENTASA® sachet4

2 x 1g PENTASA® tablets2

All Rectal preparations are Once Daily

RECTAL PREPARATIONS:
Doses-for-Remission-2-4g

1g PENTASA® enema treating left-sided disease10

1g PENTASA® suppository for treating proctitis11

*1g tablets, 1g, 2g and 4g sachets.

Images do not show medication at actual size.

HOW TO TAKE PENTASA®

PENTASA® can be taken in a variety of forms to suit patient needs

HOW TO TAKE PENTASA® ORALLY:

500mg-tablets-web

Open the PENTASA sachet with care.

500mg-tablets-web

Empty the contents into either a yoghurt or yoghurt drink and consume immediately.

500mg-tablets-web

Empty the contents of the sachet on to the tongue.

500mg-tablets-web

Wash down with water or orange juice.

HOW TO USE THE PENTASA® ENEMA:

  • Immediately before use, take the enema bottle out of the aluminium foil pack and then shake well
  • To break the seal twist the nozzle clockwise one full turn (the nozzle should then be in the same direction as before turning)
  • Put your hand in one of the disposal bags provided in the pack
  • Wrap this hand around the enema bottle
  • To administer the enema, lie on your left side with the left leg straight and the right leg bent forward for balance. The bottle content should be applied within a maximum of 30-40 seconds
  • Once the bottle is empty, withdraw the tip with the bottle still compressed
  • The enema should be retained in the administration position for 5-10 minutes until the urge to pass the enema has disappeared
  • Roll the plastic disposal bag over the empty bottle, discard it and then wash your hands

 

 

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HOW TO USE THE PENTASA® SUPPOSITORY:

 

You should make sure that you empty your bowels before inserting the suppository

  • Tear along the perforation to remove one suppository blister from a blister strip
  • Put a protector on the finger with which you will insert the suppository
  • Remove the suppository from the blister before insertion, this is done by pushing the suppository through the printed foil
  • Insertion may be easier if you moisten the suppository with water first
  • Insert the suppository gently and fully into the back passage, it may help to lie down on one side and raise the other knee
  • Remain still for a few minutes after insertion to help keep the suppository in place. If it comes out within 10 minutes, a new one should be inserted
  • Dispose of the empty blister and used finger protector safely and wash your hands
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    UK-PA-2100033 - DOP: September 2021

    • Flourie B, et al. Aliment Pharmacol Ther. 2013;37(8):767–75.
    • Pentasa Slow Release Tablets 1 g. SmPC.
    • Pentasa Sachet 1 g. SmPC.
    • Pentasa Sachet 2 g. SmPC.
    • Pentasa Sachet 4 g. SmPC.
    • Probert C.S.J, et al. J Crohn’s Colitis. 2014;8:200–7.
    • Marteau P, et al. Gut. 2005;54(7):960–5.
    • Dignass AU, et al. Clin. Gastroenterol Hepatol. 2009;7(7):762–9.
    • Bokemeyer B, et al. J Crohn’s Colitis. 2012;6:476-82.
    • Pentasa Enema 1 g. SmPC.
    • Pentasa Suppositories 1 g. SmPC.
    • Pentasa Slow Release Tablets 500 mg. SmPC.
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    Job Code: UK-PA-2000023 - Date of preparation: October 2020

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