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The following oral PENTASA® formulations are licensed for achieving and maintaining remission in children from the age of 6 and upwards: 1-4
500mg tablet
1g sachet
2g sachet
4g sachet
*PENTASA® (500mg tablets, 1g, 2g and 4g sachets) is licensed in children 6 years of age and older, and given in divided doses.
Active:
Starting – give 30-50mg per kg per day in divided doses.
Maximum dose = 75mg per kg per day in divided doses.
Total dose not to exceed 4g per day.
MAINTENANCE:
Starting – give 15-30mg per kg per day in divided doses.
Total dose not to exceed 2g per day.
Sachets can be incorporated into yoghurt or washed down with water or orange juice2-4
Granules can be washed down with water or orange juice2-4
Tablets can be broken1
Tablets can be dispersed in 50ml of cold water1
It doesn’t need to be taken at meal times because PENTASA®’s unique ethyl cellulose coated microgranules release mesalazine at all enteral pH conditions, independent of food co-administration1-16
Delivery is only slightly affected by diarrhoea1-4
Job Code: UK-PA-2000023 - Date of preparation: October 2020
