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PICOLAX® is the only bowel cleansing preparation which is indicated in children >1 and adults to clean the bowel prior to X-ray, endoscopy or surgery.1-8

PICOLAX®‘s dosing regimen is tailored to your patient’s procedure time, which means there is a shorter time between last dose of PICOLAX® and their procedure.1-9*  The tailored dosing regimen produces superior outcomes compared to the previous day-before dosing regimen.1-9

*compared to day-before dosing regimen


PICOLAX® is an effective and well-tolerated orange flavoured bowel cleanser, that benefits from the combined stimulant and osmotic effects of sodium picosulphate and magnesium citrate.10-15

The tailored dosing regimen, which is set according to the time of your patient’s colonoscopy, results in significantly less repeat colonoscopies.9*

PICOLAX® can help improve the patient experience as less medicated solution needs to be consumed compared to PEG.1-3,7,8 Additionally, patients experience reduced nausea and vomiting with PICOLAX® and find it easier to finish compared to PEG.11,16

*compared to day-before dosing regimen

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The success of any colonoscopy procedure depends upon the quality of a bowel preparation, with the time between last dose of bowel preparation and colonoscopy being instrumental to success.9

The OPTIMA Trial was a Phase III randomised, assessor-blinded, multicentre study comparing previous day-before dosing to a tailored dosing regimen.9

Hear from Professor Ralf Kiesslich, who conducted the trial, about the importance of the timings of a tailored dosing regimen and the endpoints of the OPTIMA Trial.

  • Picolax SmPC.
  • Klean-Prep SmPC.
  • Movi-Prep SmPC.
  • Fleet Phosphosoda SmPC.
  • CitraFleet SmPC.
  • Izinova SmPC.
  • Vista Prep SmPC.
  • Plenvu SmPC.
  • Kiesslich R, et al. Endoscopy Int Open. 2017;5:E282-E290.
  • Thomson J, et al. Int J Clin Pract. 2006;60(5):602–3.
  • Renaut A, et al. Colorectal Dis. 2008;10(5):503–5.
  • Gruchy S, et al. CDDW. Abstracts 2010.
  • Swarbrick MJ, et al. Clin Radiol. 1994;49(6):379–81.
  • Worthington J, et al. Curr MRes OPin. 2008;24(2):481-8.
  • MacLeod AJM, et al. Clinical Radiol. 1998;53:612–4.
  • Hamilton D, et al. BJCP. 1996;50(2):73–5.
  • NHS list price. Available at Last accessed April 2018.

Job Code: UK-PIC-2000001 - Date of preparation: January 2021


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